ObjectiveTo try to find or ascertain the clinical features of Dieulafoy disease and compare the efficacy of different methods of therapeutic endoscopy.Methods 152 cases of Dieulafoy disease diagnosed by endoscopy in 15 domestic hospitals and reported from 1992 ~ 2002 were analyzed, the results of two main treatment methods of therapeutic endoscopy-injection and electric coagulation were compared. Results In the 152 cases of Dieulafoy disease, 144 were treated with therapeutic endoscopy; 29 were treated operatively. In the 144 cases treated with therapeutic endoscopy, 88 were treated by the method of injection and 72 were succeed (72/88); 32 were treated with electric coagulation and 28 were succeed (28/32). Conclusion Therapeutic endoscopy has become the first choice of the treatment of Dieulafoy disease nowadays, the main two methods are medicine injection and electric coagulation, and there is no significant difference in the treatment efficacy between these two methods (P0.05 ).