The experiment of domestically manufactured green laser vaporization of biologic tissue under water was investigated.15 patients with benign prostatic hyperplasia(BPH) and 3 patients with urethra straitness were treated by green laser.The fast vaporization of biologic tissue under the water and the small residual layer of thermally denatured tissue were observed in this experiment.The clinical result showed that these surgical procedures have achieved a quicker operation times,a shorter post-operation catherization of the urethra times(only 2 d~3 d),good hemostasia and the lower levers of adverse side effects.So the conclusion can be drawn that green laser vaporization of tissue is a treatment method that can be adopted to treat patients with BPH,strait urethra etc urology diseases,and be safe and effective,especially can be used in patients at high risk of anesthesia.