Anti-surge control methods of centrifugal compressors were introduced.And specific anti-surge strategy for centrifugal compressors in a combined cycle power plant's gas system was put forward.Through using the surge control strategy,anti-surge can be achieved within reasonable control region.The actual operation condition of centrifugal compressors in the plant indicated that the control strategy can effectively prevent compressors from surging and ensure stable operation of the power plant.