丹参
激发子
代谢工程
化学
草药
生物合成
二萜
传统医学
生物化学
药理学
生物
医学
中医药
酶
病理
替代医学
作者
Hui Xu,Qisheng Wang,Changyong Zhou,Jianbo Xiao,Pan Liao,Guoyin Kai
出处
期刊:Journal of Medicinal Plants Research
[Academic Journals]
日期:2010-12-18
卷期号:4 (24): 2591-2597
被引量:30
摘要
Salvia miltiorrhizaBunge, called Dan shen in China, is a well-known traditional Chinese herb and has been used widely for the treatment of cardiovascular diseases due to its better performance and fewer side effects as confirmed in the long-time clinical use.Tanshinones, one class of lipid-soluble diterpene quinones from S. miltiorrhiza, were found to exhibit various pharmacological activities such as antioxidative, anti-inflammatory and anti-tumor properties.Due to the great importance of tanshinone and to its complex chemical nature as well as low content in plants, many efforts have been made to improve tanshinone production including hairy root culture, elicitor treatment and genetic engineering with new advance in recent years.Pharmacological activities of tanshinones and metabolic regulation of tanshinones biosynthesis in S. miltiorrhiza were reviewed in this paper.
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