医学
磁共振弥散成像
结节性硬化
白质
部分各向异性
有效扩散系数
磁共振成像
核医学
放射科
病理
作者
Changfu Piao,Aihong Yu,Kuncheng Li,Yuping Wang,Wen Qin,Sufang Xue
标识
DOI:10.1016/j.ejrad.2008.04.017
摘要
Purpose The purpose of this study was to investigate the features of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in cortical tubers and white-matter lesions in patients with tuberous sclerosis (TS) using diffusion tensor imaging (DTI). Materials and methods Conventional magnetic resonance imaging (MRI) and DTI were performed in 14 patients with clinically established TS. Based on these DT images, ADC and FA maps were generated. The ADC values in 32 cortical tubers, and the ADC and FA values in 18 white-matter lesions were measured and compared with those of the corresponding contralateral regions. Results Compared with the corresponding contralateral regions, cortical tubers of TS patients had significantly higher ADC values (P < 0.001); white-matter lesions had significantly higher ADC values (P < 0.001) and significantly lower FA values (P < 0.001). Conclusion DTI is a useful tool for demonstrating changes in cortical tubers and white-matter lesions resulting from TS.
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