Structures of sesquiterpenes from Curcuma longa

Five new sesquiterpenes, germacrone-13-al, 4-hydroxybisabola-2,10-diene-9-one, 4-methoxy-5-hydroxy-bisabola-2, 10-diene-9-one, 2,5-dihydroxybisabola-3,10-diene, and procurcumadiol were isolated along with curcumenone, dehydrocurdione, (4S,5S)-germacrone-4,5-epoxide, bisabola-3,10-diene-2-one, α-turmerone, bisacumol, bisacurone, curcumenol, isoprocurcumenol, zedoaronediol, procurcumenol, epiprocurcumenol and 4,5-dihydroxy-bisabola-2, 10-diene. from Curcuma longa. The structures of the new compounds were determined and the stereochemistry of 4,5-dihydroxybisabola-2,10-diene were established by spectral methods.