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Medicinal Research ReviewsVolume 12, Issue 5 p. 525-562 Article Opioid agonists and antagonists: An evaluation of their peripheral actions in inflammation Andrew Barber, Andrew Barber Department of CNS Research, E. Merck, Frankfurter Str. 250, D-6100 Darmstadt, Germany Andrew Barber: graduated from the University of Sussex in 1979 and received his Ph.D. in Neurobiology from University College of North Wales in 1984. After a stay at the University of Munich, he joined the firm E. Merck in Darmstadt as a laboratory leader, where he has been involved in testing and developing analgesics.Search for more papers by this authorRudolf Gottschlich, Rudolf Gottschlich Department of Medicinal Chemistry, E. Merck, Frankfurter Str. 250, D-6100 Darmstadt, Germany Rudolf Gottschlich: graduated from the University of Saarland in Saarbruecken in 1967 and received his Ph.D. in organic chemistry in 1970. After this he joined the firm E. Merck in Darmstadt and has worked in several areas of medicinal chemistry. Since 1988 he has been leader of a laboratory group involved in the synthesis and development of analgesic compounds.Search for more papers by this author Andrew Barber, Andrew Barber Department of CNS Research, E. Merck, Frankfurter Str. 250, D-6100 Darmstadt, Germany Andrew Barber: graduated from the University of Sussex in 1979 and received his Ph.D. in Neurobiology from University College of North Wales in 1984. After a stay at the University of Munich, he joined the firm E. Merck in Darmstadt as a laboratory leader, where he has been involved in testing and developing analgesics.Search for more papers by this authorRudolf Gottschlich, Rudolf Gottschlich Department of Medicinal Chemistry, E. Merck, Frankfurter Str. 250, D-6100 Darmstadt, Germany Rudolf Gottschlich: graduated from the University of Saarland in Saarbruecken in 1967 and received his Ph.D. in organic chemistry in 1970. After this he joined the firm E. Merck in Darmstadt and has worked in several areas of medicinal chemistry. Since 1988 he has been leader of a laboratory group involved in the synthesis and development of analgesic compounds.Search for more papers by this author First published: September 1992 https://doi.org/10.1002/med.2610120505Citations: 112 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 L. J. Rather, Bull. N.Y. Acad. Med. 47 303 (1971). CASPubMedWeb of Science®Google Scholar 2 S. D. Brain and T. J. 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