视神经脊髓炎
医学
生活质量(医疗保健)
简短疼痛清单
多发性硬化
物理疗法
横断面研究
慢性疼痛
精神科
病理
护理部
作者
Yoko Kanamori,Ichiro Nakashima,Y. Tokura,Shuhei Nishiyama,Hiroshi Kuroda,Toshiyuki Takahashi,C Kanaoka-Suzuki,Tatsuro Misu,Kazuo Fujihara,Yasuto Itoyama
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2011-08-16
卷期号:77 (7): 652-658
被引量:108
标识
DOI:10.1212/wnl.0b013e318229e694
摘要
To assess the features of pain and its impact on the health-related quality of life (HRQOL) in neuromyelitis optica (NMO).We analyzed 37 patients with NMO or NMO spectrum disorders seen at the Department of Neurology, Tohoku University Hospital, Sendai, Japan, during the period from November 2008 to February 2009. A total of 35 of them were aquaporin-4 antibody-positive. We used Short Form Brief Pain Inventory (BPI) to assess pain and Short Form 36-item (SF-36) health survey to evaluate the HRQOL. Fifty-one patients with multiple sclerosis (MS) were also studied for comparison.Pain in NMO (83.8%) was far more common than in MS (47.1%). The Pain Severity Index score in BPI was significantly higher in NMO than in MS, and patients' daily life assessed by BPI was highly interfered by pain in NMO as compared with MS. Pain involving the trunk and both legs was much more frequent in NMO than in MS. SF-36 scores in NMO were lower than MS, especially in bodily pain.Our study showed that pain in NMO is more frequent and severe than in MS and that pain has a grave impact on NMO patients' daily life and HRQOL. Therapy to relieve pain is expected to improve their HRQOL.
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