冈比亚按蚊
生物
免疫系统
疟疾
先天免疫系统
免疫
免疫记忆
疟原虫(生命周期)
按蚊
免疫学
寄生虫寄主
计算机科学
万维网
作者
Janneth Rodrigues,Fábio André Brayner,Luiz Carlos Alves,Rajnikant Dixit,Carolina Barillas-Mury
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2010-09-10
卷期号:329 (5997): 1353-1355
被引量:363
标识
DOI:10.1126/science.1190689
摘要
Mosquito Malarial Memory During their life cycle malaria parasites produce vast numbers of successive proliferative stages in their vertebrate hosts, and yet in the field most mosquitoes are free of parasites. Rodrigues et al. (p. 1353 ) report that the immune system of mosquitoes is primed early-on when the malaria parasite ( Plasmodium spp.) first crosses the mosquito gut epithelial barrier. A substantial (2- to 3.2-fold) increase in a single type of hemocyte (macrophage-like insect immune cells) is implicated in long-lived antiplasmodial immunity. This work may prove important for malaria control and for understanding immune memory in invertebrates.
科研通智能强力驱动
Strongly Powered by AbleSci AI