An Noninvasive and Impedance-Ignored Control Strategy of the Ablation Zone in Radiofrequency Ablation Therapy

This study proposed a control strategy of the ablation margin using the temperature of the probe, without causing additional damage. Compared with other methods, the proposed strategy is real time and impedance-ignored, thus has a better performance in practice. A theoretical model was established to obtain the temperature distribution during the treatment. Several functions were obtained by fitting the results of the simulation model, with which a preset central temperature curve corresponding to a desired ablation zone was determined to regulate the temperature of the control point. Considering the various impedances in practice, a voltage adjustment method according to the error between the preset central temperature and the practical central temperature was proposed to minimize the effect of impedances. At last, the strategy was verified with phantom experiments. The results show that all the temperatures of the control points reached to 50°C at a specific time and kept for a while, which demonstrated the strategy had a good performance within the error range allowed.