医学
奇纳
荟萃分析
梅德林
随机对照试验
富血小板血浆
静脉曲张
成本效益
外科
牙科
内科学
血小板
政治学
法学
精神科
风险分析(工程)
心理干预
作者
Beatriz Guitton Renaud Baptista de Oliveira,Magali Rezende de Carvalho,Andréa Pinto Leite Ribeiro
标识
DOI:10.1590/0034-7167-2018-0981
摘要
ABSTRACT Objectives: to analyze the evidence on the cost and effectiveness of Plaque Rich Plasma in the treatment of venous ulcers compared to other topical therapies. Methods: systematic review, with search in the databases: COCHRANE, EMBASE, MEDLINE via PubMed, LILACS, CINAHL, SCOPUS, without temporal cut and in the English, Portuguese and Spanish languages. Results: fifteen articles were included, a cost-minimization analysis showed that the cost of Plaque Rich Plasma is € 163.00 ± 65.90, slightly higher than the cost of standard dressing. Regarding effectiveness, the results of the studies associated with the meta-analysis suggest a tendency that Plaque Rich Plasma is effective in the healing of venous ulcers. Conclusions: it is concluded that there are few studies about the cost of Platelet Rich Plasma and this product tends to be effective in the healing of venous ulcers. However, more controlled and randomized clinical studies are necessary in order to establish a stronger recommendation.
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