A comparison study on digestion, anti-inflammatory and functional properties of polysaccharides from four Auricularia species

Four Auricularia polysaccharides (A.cornea (ACP), A.auricula (AAP), A.polytricha (APP) and M.fungus (MFP)) were researched to evaluate the effect of Auricularia species on digestion, anti-inflammatory and function of polysaccharides. The results showed that the molecular weights of ACP and MFP were significantly reduced in gastric juice from 30 min to 150 min (p < 0.05), the polysaccharides were degraded into small molecules and their structures were changed after digestion. The inhibition rate of α-amylase and α-glucosidase of APP were 71.21% and 82.01%, respectively, APP had a better hypolipidemic activity and the inhibitory activity was 89.5%. AAP, APP, and MFP could significantly promoted cell proliferation at 400 μg/mL. Four polysaccharides could inhibit inflammatory factors, so all polysaccharides have the good anti-inflammatory activity. The minimal inhibitory concentration (MIC) of APP against E. coli and S. typhi were 1.25% and 1.0%, respectively. There were significant differences in the digestion, anti-inflammatory and function of Auricularia polysaccharides among different species (p < 0.05).