Six‐Component Azido‐Ugi Reaction: from Cyclic Ketimines to Bis‐Tetrazole‐Derived 5–7‐Membered Amines

A new six‐component azido‐Ugi reaction was investigated. Using cyclic ketimines as starting materials highly efficient, synthesis of 5‐, 6‐ and 7‐membered cyclic amines connected with two tetrazole rings was elaborated. The influence of different components (ketimine, aldehyde, isocyanide) on the reaction was studied. It was demonstrated that bis‐tetrazoles derived from benzyl isocyanide can be converted efficiently to NH‐tetrazoles by hydrogenolysis.