疾病
医学
阿尔茨海默病
入射(几何)
重症监护医学
生物信息学
生物
内科学
光学
物理
作者
Pariya Khodabakhsh,Maryam Bazrgar,Leila Dargahi,Fatemeh Mohagheghi,Afsaneh Asgari Taei,Siavash Parvardeh,Abolhassan Ahmadiani
出处
期刊:Life Sciences
[Elsevier]
日期:2021-12-01
卷期号:287: 120088-120088
被引量:13
标识
DOI:10.1016/j.lfs.2021.120088
摘要
Over the last decades, our knowledge of the key pathogenic mechanisms of Alzheimer's disease (AD) has dramatically improved. Regarding the limitation of current therapeutic strategies for the treatment of multifactorial diseases, such as AD, to be translated into the clinic, there is a growing trend in research to identify risk factors associated with the onset and progression of AD. Here, we review the current literature with a focus on the relationship between gastrointestinal (GI)/liver diseases during the lifespan and the incidence of AD, and discuss the possible mechanisms underlying the link between the diseases. We also aim to review studies evaluating the possible link between the chronic use of the most common GI medications and the future risk of AD development.
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