Cascade Formation of C3‐Unsymmetric Spirooxindoles via PhI(OAc)2‐Mediated Oxidative C−C/C−N Bond Formation

Abstract A series of C3‐unsymmetric spirooxindoles were achieved by reaction of diphenylmalonamides with PhI(OAc)2 (PIDA) under metal‐free conditions. Control experiments suggest that the hypervalent iodine‐mediated reaction undergoes a cascade process involving an oxidative C−C bond formation preceeding an oxidative C−N bond formation. magnified image