Mortality, morbidity, and impact on future anaesthesia after perioperative anaphylaxis related to neuromuscular blocking agents: an 11-year single-centre retrospective study
作者
Pierre d'Heudières,Cédric Cirenei,Alexandre Bourgeois,Charlotte Geay,Laurine Cadart,Camille Potey,Julien Labreuche,Gilles Lebuffe,Damien Rousseleau
This study highlighted a significant underestimation of the incidence of perioperative anaphylaxis related to neuromuscular blocking agents and reporting to the local and national pharmacovigilance centre despite allergy assessment. Morbidity occurred in 20% of patients, primarily involving renal and cardiovascular complications, with most patients making a full recovery. The impact on subsequent anaesthesia is limited, as procedures can typically be performed without use of neuromuscular blocking agents.