医学
围手术期
麻醉
神经肌肉阻断剂
过敏反应
阻塞(统计)
回顾性队列研究
入射(几何)
罗库溴铵
神经肌肉阻滞
苏伽马德克斯
重症监护医学
药物警戒
麻醉学
丹特罗琳
梅德林
外科
镇静
全身麻醉
急诊医学
作者
Pierre d'Heudières,Cédric Cirenei,Alexandre Bourgeois,Charlotte Geay,Laurine Cadart,Camille Potey,Julien Labreuche,Gilles Lebuffe,Damien Rousseleau
标识
DOI:10.1016/j.bja.2025.07.098
摘要
This study highlighted a significant underestimation of the incidence of perioperative anaphylaxis related to neuromuscular blocking agents and reporting to the local and national pharmacovigilance centre despite allergy assessment. Morbidity occurred in 20% of patients, primarily involving renal and cardiovascular complications, with most patients making a full recovery. The impact on subsequent anaesthesia is limited, as procedures can typically be performed without use of neuromuscular blocking agents.
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