医学
接收机工作特性
逻辑回归
内科学
骨质疏松症
中性粒细胞与淋巴细胞比率
骨矿物
淋巴细胞
胃肠病学
作者
Zhang Xj,Hongyun Zhao,Duo Zhang,D. Ye,Jing Qin,Yibin Zhou,Zhang Yz
出处
期刊:PubMed
日期:2024-03-01
卷期号:28 (6): 2207-2216
标识
DOI:10.26355/eurrev_202403_35725
摘要
We investigated the associations between osteoporosis (OP) and systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) in postmenopausal women.This retrospective study included 966 postmenopausal women. Logistic regression and receiver operating characteristic curve (ROC) analyses were applied to explore the relationships between SII, NLR, MLR, and PLR with the bone mineral density (BMD) and risk of OP.Logistic regression analyses showed that SII, PLR, NLR, and MLR had independent negative associations with the OP risk. The ROC curve analysis showed that SII, NLR, and MLR predicted a low BMD, with NLR having the highest predictive value (area under the curve = 0.624). SII > 504.09, PLR > 131.87, NLR > 2.02, and MLR > 0.12 correlated with a particularly high OP risk.High levels of SII, PLR, NLR, and MLR were associated with a high OP risk. In particular, NLR > 2.02 strongly predicted the risk of OP, thereby representing a valuable and convenient inflammatory marker of the OP risk.
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