Outcomes of patients with multiple myeloma undergoing autologous transplant with suboptimal pretransplant response

There are scarce data in the literature focusing on newly diagnosed multiple myeloma (NDMM) patients who undergo autologous haematopoietic cell transplantation (autoHCT) after achieving suboptimal response to induction. To address this, we performed a retrospective, single-centre analysis of patients with NDMM who underwent upfront autoHCT between 2005 and 2021 with a pretransplant response of less than very good partial response (3 years and median OS of >8 years. Post-transplant maintenance further improved survival outcomes.