Active Gap SERS for the Sensitive Detection of Biomacromolecules with Plasmonic Nanostructures on Hydrogels

Active gap control on surface-enhanced Raman scattering (SERS) measurements is performed using tunable plasmonic nanostructures, which are fabricated through the formation of gold nanoparticle self-assembled thin films on solid substrates and their subsequent transference onto polyacrylic acid gel. When hemoproteins are used as targets, signal intensities increased more than 10-fold due to this active gap control. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.