ollagenous and Iymphocytic colitis IL,. are clinicopathologic syndromes of watery diarrhea with normal colono scopy and colonic inflammation'. Both constitute a third type of colitis after inflammatory bowel disease (1131)). Collagenous colitis(CC) shares histological and clinical similarities to lymphocytic colitis (LC), also called microscopic colitis, Thus, both diseases will be discussed here. The terminology remains somewhat controversial. The term 'microscopic colitis', while not recognized by some authorities, generally refers to a group of disorders, but still some consider microscopic colitis as synonymous to lymphocytic colitis. Because of the similarities of these two disorders, they are commonly considered a single category for the purposes of treatment and are referred to as microscopic colitis. it is not known whether LC and CC represent different clinical entities or constitute part of a spectrum of the same disease. Some said