Objective: To discuss and analyze the safety, test results and diagnostic value of Capsule endoscopy. Methods: The clinical data of 120 patients and healthy individuals receiving capsule endoscopy examinations in our hospital from January 2011 and April 2013 were collected and analyzed. Results: All the patients were successfully checked. The detection rate of obscure gastrointestinal bleeding, chronic abdominal pain and healthy individuals were 82.76 %, 59.26 % and 40.90% respectively. 4 cases of colon polyps were detected in Colonoscopy-negative patients. 4 cases of Organic diseases in small intestinal were detected in patients with irritable bowel syndrome. Conclusion: Capsule endoscopy was a safe and well-tolerable method to examine and diagnose the intestinal disease.Capsule endoscopy was superior to convention methods in examining and diagnosing the patients with chronic abdominal pain and obscure gastrointestinal bleeding. There was a certain value of Capsule endoscopy to distinct functional gastrointestinal disorders with organic diseases and screen intestinal disease.