Review on Epidemiological Studying Strategy and Molecular Genetics of Diabetes Mellitus

Epidemiology is not only an important basic subject but also a wide range of applied science in area of modern medicine.As a methodology,Epidemiology has an irreplaceable role in the research of complex diseases.With a complex disease property,DM should be studied with systemic and multi-level epidemiological methods.In this article,we systematically reviewed the studying works on DM from the 3 aspects of clinical epidemiology,genetic epidemiology and molecular epidemiology,which branched from clinical medicine,genetics and molecular biology respectively,the candidate genes of DM were also enumerated in the aspect of molecular genetics.We proposed that DM should be systematically explored with the methods of combining the macro-epidemiology(influences come from the society and environment) and micro-epidemiology(molecular genetics).