医学
经皮
卵圆孔未闭
磁共振成像
导管
卵窝
放射科
左心房
心脏病学
心房颤动
作者
Arno Buecker,Elmar Spuentrup,R. G. Grabitz,Franz Freudenthal,Eberhard G. Muehler,Tobias Schaeffter,J. J. Van Vaals,Rolf W. Günther
出处
期刊:Circulation
[Ovid Technologies (Wolters Kluwer)]
日期:2002-07-23
卷期号:106 (4): 511-515
被引量:90
标识
DOI:10.1161/01.cir.0000023621.88708.62
摘要
Percutaneous closure of the patent foramen ovale (PFO) is usually performed under x-ray in combination with ultrasound guidance. We tested the feasibility of applying magnetic resonance (MR) guidance for percutaneous closure of PFO in an animal model, thus avoiding the disadvantage of ionizing radiation.Real-time MRI with radial or spiral k-space filling (15 frames per second) on an interventional 1.5-T high-field whole-body system was exploited to examine the feasibility of MR-guided closure of the PFO in 7 piglets weighing approximately 14 kg. A specially designed prototype nonmagnetic closure device was introduced via the femoral vein. The short bore of the magnet and in-room monitors allowed for visualization and steering of the catheter with the loaded occluder. Catheterization of the left atrium and, finally, correct placement of the device was possible in all animals. Deployment of the device was depicted by real-time MR, and initial misplacement, which occurred in 2 animals, was easily detected and corrected.Real-time MR guidance of PFO closure, without the use of ionizing radiation, is feasible in an animal model.
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