医学
滑膜炎
免疫学
癌症研究
Janus激酶2
磷酸化
受体
关节炎
内科学
细胞生物学
生物
作者
Mar Carrión,Yasmina Juarranz,Carmen Martínez,Isidoro González‐Álvaro,José L. Pablos,Irene Gutiérrez‐Cañas,Rosa P. Gomariz
出处
期刊：Rheumatology
[Oxford University Press]
日期：2013-09-19
卷期号：52 (12): 2177-2186
被引量：75
标识
DOI：10.1093/rheumatology/ket315
摘要
Therapies based on the pharmacological disruption signalling of IL-22 could be beneficial for the treatment of rheumatic diseases. The restricted expression of IL-22R1 to non-lymphoid cells could lead to a reduction of side effects mediated by immune responses.
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