氧化应激
医学
脑出血
薄壁组织
炎症
自噬
生物信息学
麻醉
病理
内科学
蛛网膜下腔出血
生物
细胞凋亡
生物化学
作者
Linqian Shao,Sichao Chen,Li Ma
标识
DOI:10.3389/fncel.2022.853589
摘要
Intracerebral hemorrhage (ICH) is a clinical syndrome in which blood accumulates in the brain parenchyma because of a nontraumatic rupture of a blood vessel. Because of its high morbidity and mortality rate and the lack of effective therapy, the treatment of ICH has become a hot research topic. Meanwhile, Oxidative stress is one of the main causes of secondary brain injury(SBI) after ICH. Therefore, there is a need for an in-depth study of oxidative stress after ICH. This review will discuss the pathway and effects of oxidative stress after ICH and its relationship with inflammation and autophagy, as well as the current antioxidant therapy for ICH with a view to deriving better therapeutic tools or targets for ICH.
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