化学
生物分析
活性成分
生化工程
纳米技术
色谱法
药理学
医学
材料科学
工程类
作者
Natalia Manousi,Paraskevas D. Tzanavaras,Constantinos K. Zacharis
标识
DOI:10.1016/j.jpba.2022.114921
摘要
Although almost 60 years have passed since their first application, bisphosphonates are still in use as medicine against osteoporosis. Due to their chemical structures and properties, these compounds have attracted the attention of many scientists. From an analytical point of view, various analytical methods have been published in the last decade for the determination of these drugs involving separation techniques (HPLC, GC, CE), electrochemical, sensors, spectrophotometry, IR, etc. The present article is a continuation of the 2008 review article of the authors on the analysis of bisphosphonates (C.K. Zacharis, P.D. Tzanavaras, JPBA 48 (2008) 483-496) and it focuses on bioanalytical and pharmaceutical QC applications on the analysis of this class of pharmaceutically active compounds presenting a critical discussion on advantages/disadvantages, figures of merit and analytical features of techniques and methods on this topic.
科研通智能强力驱动
Strongly Powered by AbleSci AI