Photoelectrochemical sensor based on nickel phthalocyanine–based metal–organic framework for sensitive detection of Curcumin

A novel photoelectrochemical (PEC) sensor based on a nickel phthalocyanine-based metal organic framework (NiPc–Ni MOF) was prepared and used to detect Curcumin. The photosensitive material NiPc–Ni MOF was synthesized and characterized via scanning electron microscopy, transmission electron microscopy, and X-ray diffraction. Under white light irradiation, the NiPc–Ni MOF composite modified indium tin oxide glass electrode showed a good photocurrent response to the detection of Curcumin. The experimental conditions of a light source, pH, bias voltage, modifier concentration, and coating amount were optimized. The improved PEC sensor showed a linear range of 0.0025–16 μM and a detection limit of 0.8 nM. Moreover, the PEC sensor exhibited good stability, selectivity, and reproducibility. Finally, the PEC sensor was used to detect Swisse Curcumin tablets with satisfactory results. The method presented in this study is a new strategy for detecting Curcumin.