Silver or copper-catalyzed ring opening [3+2] annulation of 2-polyfluoroalkyl chromones/6-polyfluoroalkyl pyran-4 H -ones with methylene isocyanides: regioselective synthesis of 3-polyfluoroalkyl pyrroles

In this work, we present a synthetic protocol for the preparation of polysubstituted 3-trifluoromethyl(polyfluoroalkyl)pyrroles.