pH‐Responsive Probiotic‐Liposome Hybrid System Synergistically Treats Radiation‐Induced Injury via Dual Mechanisms of Anti‐Inflammatory and Microbiome Modulation (Adv. Healthcare Mater. 19/2025)

Probiotic-Liposome Hybrid System In article 2501642, Zhe Lei, Lingchuan Guo, Lin Hu , and co-workers develop an oral pH-responsive probiotic-liposome hybrid (EcNPIN-L) by conjugating Escherichia coli Nissle 1917 with pinocembrin-loaded liposomes via biotin-streptavidin binding, coated in Eudragit L100-55. It releases components at intestinal pH, and synergizes pinocembrin's anti-inflammatory effects with probiotic activity.