Electrochemical sensor for luteolin detection

This study developed an electrochemical sensor based on a nitrogen-doped hollow carbon sphere @ZIF-8 composite material (NC@ZIF-8), designed to efficiently detect the natural flavonoid luteolin. The composite material combines the high conductivity of hollow carbon spheres with the large specific surface area of ZIF-8. By optimizing the synthesis process and electrode modification conditions, the sensitivity and selectivity of the sensor were significantly enhanced. Experimental results show that the sensor exhibits excellent detection performance over a wide linear range (0.05–30 μM), with a detection limit as low as 0.011 μM. It also demonstrates good interference resistance and stability. The recovery rates for actual samples (Honeysuckle extract and watermelon juice) ranged from 95.41% to 101.20%, confirming its practical value in food safety and drug analysis. Luteolin is a natural compound found in many plants and fruits, known for its health benefits. Researchers developed a new, simpler method using electrochemical sensors made from special materials called NC@ZIF-8 composites. These materials combine nitrogen-doped hollow carbon spheres with ZIF-8, a type of metal-organic framework (MOF) known for its unique properties like high surface area and conductivity. The team synthesized these materials and used them to create sensors that can quickly and accurately detect luteolin. They tested the sensors’ performance using various techniques and optimized conditions to ensure reliability. The sensors showed excellent results in detecting luteolin even in the presence of other substances, proving their effectiveness. The study concludes that these new sensors are a promising tool for detecting luteolin in real-world samples like honeysuckle extract and watermelon juice. This summary was initially drafted using artificial intelligence, then revised and fact-checked by the author. This study developed an electrochemical sensor based on a nitrogen-doped hollow carbon sphere @ZIF-8 composite material (NC@ZIF-8), designed to efficiently detect the natural flavonoid luteolin. The composite material combines the high conductivity of hollow carbon spheres with the large specific surface area of ZIF-8. By optimizing the synthesis process and electrode modification conditions, the sensitivity and selectivity of the sensor were significantly enhanced. Experimental results show that the sensor exhibits excellent detection performance over a wide linear range (0.05–30 μM), with a detection limit as low as 0.011 μM. It also demonstrates good interference resistance and stability. The recovery rates for actual samples (Honeysuckle extract and watermelon juice) ranged from 95.41% to 101.20%, confirming its practical value in food safety and drug analysis.