ETS1型
癌症研究
基因敲除
甲状腺乳突癌
转录因子
生物
发起人
分子生物学
甲状腺癌
基因
基因表达
癌症
遗传学
作者
Yiyi Xu,Jiwei Gao,Na Wang,Jan Zedenius,Inga‐Lena Nilsson,Weng‐Onn Lui,Dawei Xu,C. Christofer Juhlin,Catharina Larsson,Ninni Mu
标识
DOI：10.1210/clinem/dgae589
摘要
BRAFV600E and TERT promoter mutations in papillary thyroid carcinoma (PTC) have a synergistic effect on prognosis. This effect is believed to arise from MAPK activation triggered by BRAFV600E, leading to the upregulation of ETS transcription factors that bind to the mutant TERT promoter.
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