失调
微生物群
银屑病
特应性皮炎
发病机制
肠道微生物群
肠道菌群
免疫学
生物
医学
内分泌系统
功能(生物学)
肠道微生物群
基因组
生物信息学
遗传倾向
人类微生物组计划
菌群(微生物学)
微生物学
人体微生物群
益生菌
作者
Izabella Ryguła,Wojciech Pikiewicz,Beniamin Oskar Grabarek,Michał Wójcik,Konrad Kaminiów
摘要
Dermatoses are an increasingly common problem, particularly in developed countries. The causes of this phenomenon include genetic factors and environmental elements. More and more scientific reports suggest that the gut microbiome, more specifically its dysbiosis, also plays an important role in the induction and progression of diseases, including dermatological diseases. The gut microbiome is recognised as the largest endocrine organ, and has a key function in maintaining human homeostasis. In this review, the authors will take a close look at the link between the gut–skin axis and the pathogenesis of dermatoses such as atopic dermatitis, psoriasis, alopecia areata, and acne. The authors will also focus on the role of probiotics in remodelling the microbiome and the alleviation of dermatoses.
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