Vitamin E Supplementation in Pediatric Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease is the most common type of liver disease seen in children. Development and progression of the disease are linked to oxidative injury and stress. Improving antioxidant-oxidant balance as an interventional strategy for the management and treatment of pediatric nonalcoholic fatty liver disease has been studied. Because of concerns of inadequate vitamin E consumption and status among children and adolescents, this review explores how supplemental vitamin E, in conjunction with lifestyle modification, can influence pediatric nonalcoholic fatty liver disease progression and treatment.