Single-Walled Carbon Nanotubes as a Support for Palladium-Catalyzed Aquachemical Cross-Coupling Reactions

We developed SWNT-supported palladium catalysts that enable cross-couplings in water without surfactants or cosolvents. Even water-insoluble solid aryl bromides reacted efficiently with simple stirring. Pyrene-1-sulfonate anchoring ensured high activity, recyclability, and undetectable leaching. Unlike mechanochemical methods, our stirring protocol avoids energy-intensive steps. This strategy highlights the intrinsic advantages of SWNTs in stabilizing reactive metal species, offering a sustainable and versatile platform for advancing redox-active organometallic chemistry in water.