多发性骨髓瘤
医学
中性粒细胞减少症
抗体
淋巴瘤
双特异性抗体
临床试验
免疫学
细胞因子释放综合征
血液学
肿瘤科
内科学
化疗
免疫疗法
单克隆抗体
免疫系统
嵌合抗原受体
作者
Hind Rafei,Katayoun Rezvani
摘要
Bispecific antibodies have shown significant clinical efficacy in patients with relapsed/refractory B‐cell non‐Hodgkin lymphomas and multiple myeloma, expanding treatment options for these patients. While these advancements are promising, it is important to be aware of associated side effects, such as cytokine release syndrome, neutropenia and infections. Gonugunta et al. provide valuable insights into the infection risks linked to the use of bispecific antibodies in haematological malignancies, drawing on both clinical trial data and real‐world experiences. Commentary on: Gonugunta et al. Risk of infections with bispecific antibodies in B‐cell non‐Hodgkin lymphomas and multiple myeloma—The current state. Br J Haematol 2024; 205:1197‐1201.
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