Light and immunostimulant mediated <i>in situ</i> re-education of tumor-associated macrophages using photosensitizer conjugated mannan nanoparticles for boosting immuno-photodynamic anti-metastasis therapy

Novel co-operative immuno-photodynamic therapy nanoparticles, targeting tumor-associated macrophages, modulating the tumor microenvironment, and preventing tumor metastasis by skewing TAMs to M1-like cells, have been developed.