Light‐Regulated P(VDF‐TrFE)/Bi2S3 Microneedle Patch with Tunable Electric Stimulation for Modulating the Healing of Burn Wound Dynamically

, generating photoexcited electrons under near-infrared (NIR) light illumination, the electric property of the MN patch is easily adjustable to provide stage-optimized electrical stimulation. In vitro experiments show that the P(VDF-TrFE)/Bi₂S₃ microneedle patches, proving the inherent polarized bound charges of P(VDF-TrFE) and the photoexcited electrons generated by Bi₂S₃, can regulate cell behaviors associated with different stages of burn wound healing, including macrophage polarization, angiogenesis, and collagen deposition. In vivo, experiments reveal that persistent bound charges and stage-optimized photo-electrical stimulation synergistically accelerate wound healing, while the physical intervention of microneedles reduces scar tissue formation. This microneedle patch, which provides variable electrical stimulation, offers a promising strategy for enhanced burn healing.