Tmprss6 modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway

This study unveils intricate mechanistic pathways activated by Tmprss6 silencing, amplifying p53 expression, facilitating hepatocyte apoptosis, and accelerating RILI progression, which providing nuanced insights into the multifaceted involvement of Tmprss6 in RILI.