医学
阻塞性睡眠呼吸暂停
呼吸暂停
睡眠呼吸暂停
睡眠(系统调用)
急诊医学
重症监护医学
儿科
医疗急救
心脏病学
内科学
计算机科学
操作系统
作者
Adrian Davies,Nikhil Jaganathan,Yeilim Cho,Xiaoyue Liu,Sara J. Healy,Younghoon Kwon,William Healy
标识
DOI:10.14423/smj.0000000000001838
摘要
Obstructive sleep apnea (OSA), a condition with high prevalence, is characterized by reduced dilatory function of pharyngeal muscles, which can be influenced by upper airway narrowing, dilator muscle dysfunction, respiratory dysfunction, and genetics. Three of the most clinically important phenotypes of OSA include disturbed sleep, excessive sleepiness, and minimal symptoms, with varying implications for management and morbidity. This article reviews current perspectives on these OSA phenotypes, as well as the process of confirming a diagnosis of OSA. Lastly, this article delineates various current and future OSA therapy approaches through review and analysis of the existing literature with discussion on the outlook for OSA treatment.
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