昼夜节律
生物
预测(人工智能)
时辰疗法(睡眠期)
白色脂肪组织
内生
脂肪组织
疾病
内分泌学
生物信息学
生理学
内科学
医学
计算机科学
人工智能
作者
Kaiming Yue,Patrick C.N. Rensen,Sander Kooijman
标识
DOI:10.1016/j.gde.2023.102056
摘要
White and brown adipose tissues are highly dynamic organs anticipating and responding to changes in the environment. The circadian timing system facilitates anticipation, and it is therefore not surprising that circadian disturbances, a prominent feature of modern 24/7 society, increase the risk for (cardio)metabolic diseases. In this mini-review, we will address mechanisms and strategies to mitigate disease risk associated with circadian disturbances. In addition, we discuss the opportunities arising from the knowledge we gained about circadian rhythms in these adipose tissues, including the application of chronotherapy, optimizing endogenous circadian rhythms to allow for more effective intervention, and the identification of novel therapeutic targets.
科研通智能强力驱动
Strongly Powered by AbleSci AI