化学
石墨烯
黄曲霉毒素
氧化物
同种类的
电化学
对偶(语法数字)
组合化学
纳米技术
色谱法
物理化学
有机化学
电极
食品科学
艺术
材料科学
物理
文学类
热力学
作者
Handong Yao,Shuxin Du,Lu Yang,Yifeng Ding,Hui Shan,Yi Qiu,Ge Dai,Fengfeng Mo
出处
期刊:Talanta
[Elsevier]
日期:2024-06-01
卷期号:273: 125915-125915
标识
DOI:10.1016/j.talanta.2024.125915
摘要
Aflatoxin (AFs) contamination is one of the serious food safety issues. Aflatoxin B1 (AFB1) is the most common and toxic aflatoxin, which has been classified as a class 1 carcinogen by the International Agency for Research on Cancer (IARC). It is extremely destructive to liver tissue. Developing a convenient and sensitive detection technique is essential. In this paper, we developed a homogeneous dual recognition strategy based electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1 (AFB1) based on the magnetic graphene oxide (MGO) and UiO-66. The MGO was synthesized for the recognition and magnetic separation of AFB1 from complex samples. UiO-66/ferrocenecarboxylic acid (Fc)/aptamer composites were constructed as both recognition and signal probes. The probes would specifically capture AFB1 enriched by MGO, which enables dual recognition in homogeneous solution, thus further improving the accuracy of AFB1 detection. The electrochemical aptasensor for AFB1 had a linear range from 0.005 to 500 ng mL−1. Additionally, the limit of detection was 1 pg mL−1. It shows a favorable potential for both sensitive and accurate detection of AFB1 in real samples.
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