握力
硒
医学
肌肉力量
内科学
体质指数
心力衰竭
萧条(经济学)
手部力量
肌萎缩
老年学
物理疗法
心脏病学
化学
宏观经济学
经济
有机化学
作者
Justine Beck,Luigi Ferrucci,Kai Sun,Jeremy D. Walston,Linda P. Fried,Ravi Varadhan,Jack M. Guralnik,Richard D. Semba
出处
期刊:Biofactors
[Wiley]
日期:2007-01-01
卷期号:29 (1): 37-44
被引量:56
标识
DOI:10.1002/biof.5520290104
摘要
Aging is associated with a loss of muscle strength, and, in turn, loss of muscle strength has been associated with increased risk of frailty, disability and mortality. The factors that contribute to loss of muscle strength with aging have not been well characterized. Selenium is important in normal muscle function because of its role in selenoenzymes that protect muscle against oxidative damage. We hypothesized that low serum selenium concentrations were associated with poor grip strength. We examined the association between serum selenium and hand grip strength among 676 moderately to severely disabled community-dwelling women in the Women's Health and Aging Study I in Baltimore, Maryland. After adjusting for age, race, body mass index, Mini-Mental Status Examination score, current smoking, hypertension, congestive heart failure and depression, serum selenium was associated with grip strength (P=0.04). This study supports the idea that selenium is important to muscle strength in older women.
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