Management of Low Birth Weight Infants with Congenital Heart Disease

Low birth weight infants with congenital heart disease (CHD) have a higher mortality risk and likely a higher morbidity risk than their preterm or appropriate for gestational age counterparts without CHD and term counterparts with CHD. As our understanding of the pathophysiology and treatment of the diseases associated with prematurity and growth restriction improves, the outcomes for these infants should continue to improve. In addition, as more of these infants survive and are referred for surgery, operative techniques and strategies are likely to continue to improve. At this time, there is no adequate evidence that mortality is improved by delaying surgery for weight gain or performing palliative operations initially. Given the challenging physiology in this population, optimal management includes early referral to a tertiary or quaternary facility and a multidisciplinary team approach consisting of cardiologists, neonatologists, surgeons, nurses, perfusionists, and anesthesiologists.