清脆的
回文
Cas9
DNA
质粒
生物
核酸内切酶
计算生物学
遗传学
基因
作者
Nadrian C. Seeman,Neville R. Kallenbach
出处
期刊:Annual Review of Biophysics and Biomolecular Structure
[Annual Reviews]
日期:1994-06-01
卷期号:23 (1): 53-86
被引量:155
标识
DOI:10.1146/annurev.bb.23.060194.000413
摘要
Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
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