An Efficient and Facile Access to Substituted 1E,3E-DienylphosphonatesviaHorner-Wadsworth-Emmons Olefination of α,β-Unsaturated Aldehydes with Tetraethyl Methylenebisphosphonate

An operationally simple and high-yielding synthetic method for 1E,3E-dienylphosphonates has been developed through the Horner-Wadsworth-Emmons olefination of α,β-unsaturated aldehydes with tetraethyl methylenebisphosphonate, in heterogeneous medium, in the presence of solid potassium carbonate, in refluxing DMF. An operationally simple and high-yielding synthetic method for 1E,3E-dienylphosphonates has been developed through the Horner-Wadsworth-Emmons olefination of α,β-unsaturated aldehydes with tetraethyl methylenebisphosphonate, in heterogeneous medium, in the presence of solid potassium carbonate, at refluxing DMF.