Effects of zolpidem on polysomnography in patients with insomnia

AIM:To observe the effects of zolpidem on polysomnography (PSG) in patients with insomnia.METHODS:Twenty-six patients with insomnia received PSG in three consecutive night and received zolpidem 20 mg before sleep on night 3.Thirty-three normal subjects received PSG on an adaptation night and a baseline night.RESULTS:Compared with baseline night,sleep efficiency of patients with insomnia improved (P0.05),awakening time reduced (P0.01),stage 1 time decreased (P0.01),stage 2 time increased (P0.01 ),sleep latency shortened (P0.01) on night 3.CONCLUSION:Zolpidem has effects on PSG in patients with insomnia.