Ginsenosides are major active ingredients of ginseng. The Pharmacologic effects of ginsenosides are various. The pharmacologic effects of individual ginsenoside have been studied deeply now, especially focusing on regulation of metabolism. In this article, we reviewed progresses in studies on pharmacologic effects of ginsenosides in recent years in the world, referring to nervous system, small intestinal transit, endocrine system,immune system, signal transduction, anti-aging, hemolysis, burn wound healing, synergy of anti-tumor, human sperm motility, drug metabolism enzyme and lowering plasma glucose. Furthermore, protopanaxadiol-type ginsenosides were compared with protopanaxatriol-type ginsenosides on the pharmacologic effects briefly.