The base of model - making constrained by facies, which is one of important sandstone reservoir model -making methods, is the prediction of the advantageous reservoir facies. It should be defined by the study of sedimentary microfacies and diagenesis. Complicated diagenesis had happened in the low - permeability sandstone reservoir which mainly controls the distribution of advantageous reservoir facies. In the case of Es3 low - permeability sandstone reservoir in third region of Bonan oil field, the article illustrated the study method of low - permeability sandstone reservoir diagenesis, divided three kind of diagenesis - reservoir facies and pointed out the advantageous reservoir facies, which is the base of model - making constrained by facies.