Preliminary Study on the Processing Mechanism of Polygonum multiflorum Thunb by Microbial Fermentation

The aim of this study was to investigate the processing mechanism of Polygonum multiflorum Thunb by microbial fermentation.The anthraquinones and di-phenyl ethylene glycoside in fermented and no-fermented samples were determined by HPLC, and emodin-6-O-β-D-glucopyranoside was produced in P.multiflorum after fermentation.However,no evident change was identified for di-phenyl ethylene glycoside.In addition,the contraction action of the emodin-6-O-β-D-glucopyranoside was weaker than that of emodin on excised rabbit ileum,which suggested that the purgative activity of P.multiflorum was reduced after fermentation.The results preliminarily indicate that the processing for P.multiflorum by microbial fermentation is scientific.