吡啶
氨基脲
吡啶
化学
羟基化
节杆菌
醛
分解
阿尔法(金融)
哌啶
新陈代谢
药物化学
立体化学
有机化学
生物化学
酶
患者满意度
结构效度
催化作用
护理部
医学
出处
期刊:PubMed
日期:1974-09-01
卷期号:11 (3): 192-200
被引量:8
摘要
An organism, which degrades alpha-picoline but also utilizes 2-ethylpyridine or piperidine as alternative growth substrates, has been isolated from soil and characterized as arthrobacter sp. alpha-picoline-grown cells oxidize 2-ethylpyridine and vice versa. Other pyridine derivatives tested are neither utilized as growth substrates nor oxidized by the organism. alpha-Picolinate and 2-hydroxy-6-methylpyridine are not metabolized, indicating that degradation is neither initiated by methyl oxidation nor by hydroxylation in the 6-position of pyridine ring. Succinate semi-aldehyde and pyruvate accumulate when alpha-picoline oxidation by resting cell suspensions is blocked by semicarbazide. The Arthrobacter grown on alpha-picoline rapidly oxidizes succinate semi aldehyde...
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